36 quotes found
Neuropsychiatrist · American · 2000
American neuropsychiatrist
“What biological processes enable me to review my own history with such emotional vividness?”
“As knowledge advances and scientific disciplines change, so do the disciplines impinging on them.”
“The firing of individual nerve cells involved in perceptual and motor processing is modified by attention and decision making.”
“The same CREB switch is important for many forms of implicit memory in a variety of other species, from bees to mice to people.”
“Modernism in Vienna brought together science and culture in a new way to create an Age of Insight that emphasized a more complex view of the human mind than had ever existed before.”
“In art, as in science, reductionism does not trivialize our perception - of color, light, and perspective - but allows us to see each of these components in a new way.”
“You could double the number of synaptic connections in a very simple neurocircuit as a result of experience and learning. The reason for that was that long-term memory alters the expression of gene...”
“The problem of psychoanalysis is not the body of theory that Freud left behind, but the fact that it never became a medical science. It never tried to test its ideas.”
“I went to medical school after having decided to do so somewhere between my junior and senior year at Harvard - very late. I initially wanted to be an intellectual historian.”
“When I was a medical student in the 1950s, we practically never spoke about Alzheimer's disease. And why is that so? And that is because people didn't live long enough to have Alzheimer's disease.”
“In the period from 1920 to 1960, psychiatry derived its main intellectual impetus from psychoanalysis. During this phase, its most powerful antidisciplines were philosophy and the social sciences. ...”
“In the near future, neurobiology will address a matter of more general and fundamental importance: the biology of human mental processes. ...Psychology and psychiatry can illuminate and define for ...”
“The Age of Insight is a product of my... fascination with the intellectual history of Vienna from 1890 to 1918, as well as my interest in Austrian modernist art, psychoanalysis, art history, and th...”
“Five separate pulses of serotonin, designed to simulate five shocks to the tail, strengthened the synaptic connection for days and led to the growth of new synaptic connections... that did involve ...”
“Jacques Monod... published a paper entitled Genetic Regulatory Mechanisms in the Synthesis of Protein. Using bacteria as a model system, they made the remarkable discovery that genes can be regulat...”
“What is learning but a set of sensory signals from the environment, with different forms of learning resulting from different types or patterns of sensory signals?”
“Jacob and Monod found that in bacteria, genes are switched on and off by other genes. This led them to distinguish between effector genes and regulatory genes. Effector genes encode effector protei...”
“Jacob and Monod not only outlined a theory of gene regulation, they also discovered the first regulators of gene transcription. These regulators come in two forms—repressors, genes that encode the ...”
“In the Jacob-Monod model, signals from a cell's environment activate regulatory proteins that switch on the genes encoding particular proteins. This led [Philip] Goelet and me to wonder whether the...”
“Even though I had long been taught that the genes of the brain are the governors of behavior, the absolute masters of our fate, our work showed that, in the brain as in bacteria, genes are also ser...”
“CREB's opposing regulatory actions provide a threshold for memory storage, presumably to ensure that only important, life-serving experiences are learned. Repeated shocks to the tail are a signific...”
“Exceptionally good memory exhibited by some people may stem from genetic differences in CREB-2 that limit the activity of this repressor protein in relation to CREB-1.”